Looking for a Prolozone Therapy Specialist in NYC?

About Prolozone Therapy

Prolozone therapy is a regenerative needling procedure that injects a combination of procaine, anti-inflammatory medications, vitamins, minerals, and a mixture of ozone/oxygen gas into joints or tissues that have been injured or have degenerated. Tendons and connective tissues surrounding the joint capsule typically have extremely low vascularity, which limits the amount of blood and nutrients that can reach the site of injury.

When injected, the Prolozone solution quickly reduces pain and inflammation while stimulating the body’s innate healing mechanisms, giving the healing process a jump-start. We use our high resolution ultrasound equipment to guide the injection procedure with precsion. We then confirm and monitor the healing process using superb microvascular imaging (SMI) . SMI allows us to detect activity in microscopic blood vessels, to confirm successful Prolozone therapy results.

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Dr. Lev Kalika, Best Rated Regenerative
Therapy Doctor in Manhattan

Dr. Kalika, NYDNRehab clinical director, has devoted his life’s work to finding the most advanced and effective therapies and technologies for treating musculoskeletal pain syndromes and movement disorders. His dedication to successful patient outcomes has earned him international recognition as a sports medicine practitioner.

Technology has played a major role in Dr. Kalika’s success. In particular, the use of high-resolution research-grade ultrasonography for diagnosis and treatment dramatically enhances patient outcomes by eliminating guesswork and providing top-grade tools for accurate treatment. Dr. Kalika has published multiple scientific studies on the use of ultrasound for diagnosis, and for ultrasound-guided therapeutic procedures.

Prolozone therapy is one of several regenerative approaches used at NYDNRehab to reduce pain and inflammation, and accelerate the healing of damaged tissues. Dr. Kalika applies his expertise in ultrasound guidance to make Prolozone therapy and other needling procedures safe, accurate and effective.

Get Superior Prolozone Therapy at

Prolozone injection procedures are typically performed “blind,” relying on the skills and expertise of practitioners, under the assumption that the patient’s anatomy conforms to the standard human anatomical model. At NYDNRehab, we understand that every patient is unique, and that the architecture of anatomical structures can vary greatly from one patient to the next.

Our personalized one-on-one treatment sets NYDNRehab apart from other physical therapy clinics. We treat the patient, not the symptoms. For that reason, we use high-resolution ultrasound to guide our needling procedures. Ultrasound guidance ensures that the needle precisely hits its mark, eliminating the need for multiple injections and dramatically increasing the success rate of Prolozone therapy.

High resolution diagnostic ultrasound lets us visualize damages in the fascia, muscles and joint capsule in real time, with the patient in motion. With ultrasound imaging, we can determine exactly where the Prolozone solution needs to be injected.

Another advantage of our cutting-edge ultrasound equipment is technology that enables sonoelastography, providing us with information on tissue density and elasticity, crucial properties that help us localize your Prolozone injection. In addition, superb microvascular imaging (SMI), another feature of our expert-class equipment, lets us detect early signs of healing and track the healing process.

An abundance of research affirms that ultrasound guided injections are by far superior to and more precise than blind injections. Our use of advanced technologies in Prolozone therapy ensures more effective treatment and faster healing.

Prolozone Specialist

More Regenerative Therapies at

At NYDNRehab, we understand the power of the human body to heal itself. Our non-invasive regenerative therapies and minimally invasive needling therapies are designed to stimulate the body’s own healing mechanisms and accelerate the healing process. In addition to Prolozone therapy, we offer a stellar array of regenerative therapies, rarely found in run-of-the-mill physical therapy clinics.

Focused Extracorporeal Shock Wave Therapy (ESWT)

Focused ESWT is used as a regenerative treatment for damaged tendon, muscle and bone tissue. This technology produces high frequency sound waves to stimulate the body’s own reparative mechanisms. It is especially effective for chronic degenerative tendon disorders and myofascial pain syndrome.

Extracorporeal Magnetic Transduction Therapy (EMTT)

EMTT is a fairly new technology that transmits high energy magnetic pulses to targeted tissues. The magnetic waves synchronize with the body’s own magnetic fields, causing a disturbance that triggers a regenerative response. EMTT waves can penetrate deep tissues up to 18 cm beneath the skin’s surface, to target difficult-to-reach tendons, muscles, bones and nerves.

Extracorporeal Pulse Activation Technology (EPAT)

Extracorporeal Pulse Activation Technology (EPAT)

Extracorporeal Pulse Activation Technology (EPAT)

EPAT, also known as defocused shock wave therapy, uses acoustic pressure waves to enhance blood circulation to targeted tissues. This speeds up the delivery of oxygen and nutrients to damaged tissues and stimulates cellular metabolism, to accelerate the healing process.

High Energy Inductive Therapy (HEIT)

HEIT uses electromagnetic fields to penetrate cells, tissues, organs and bones, to reactivate the electrochemical function of cells and cell membranes. HEIT generates a magnetic field 600 times stronger than the field of a normal magnet, to stimulate healing of nerves, muscles and blood vessels.

INDIBA CT9 Radiofrequency Device

INDIBA CT9 Radiofrequency Device

Our INDIBA Tecar therapy machine converts electrical current into a stable radio frequency current of 448 kHz, designed to increase and stabilize the exchange of ions in damaged cells, evoking a regenerative response that accelerates healing. INDIBA can be used to successfully treat joint and muscle disorders, low-back pain, sports injuries, surgical incisions and various pain syndromes. Another therapeutic effect of INDIBA is extreme and prolonged cellular hyperthermia. Due to this effect, INDIBA therapy combined with manual therapy and soft tissue tissue manipulation enables instantaneous release to occur, significantly shortening the number and duration of physical therapy sessions. What is normally accomplished in two months of physical therapy can be accomplished in 3-4 sessions with INDIBA.

Ultrasound Guided Dry Needling

Myofascial trigger points often contribute to lower back pain. Dry needling is an outpatient procedure that inserts non-medicated needles into the trigger point to evoke a twitch response, releasing the trigger point and immediately relieving pain. Ultrasound guidance eliminates the need for multiple insertions, reducing pain and discomfort for the patient.

Regenerative Ultrasound Guided Injection Therapies

Ultrasound Guided Injection

Injection therapies use natural/neutral solutions that stimulate cellular repair by either nourishing or irritating the targeted cells. Guidance by ultrasound ensures that the injected substances hit their mark, for maximum effectiveness.

Focused Shockwave Therapy

Platelet Rich Plasma (PRP)

PRP therapy uses a sample of the patient’s own whole blood, which is spun in a centrifuge to extract a high concentration of platelets. When injected into damaged tissues, PRP initiates tissue repair by releasing biologically active factors such as growth factors, cytokines, lysosomes and adhesion proteins. The injected solution stimulates the synthesis of new connective tissues and blood vessels. PRP can help to jump-start healing in chronic injuries and accelerate repair in acute injuries.

Proliferation Therapy, aka Prolotherapy

Prolotherapy uses a biologically neutral solution, often containing dextrose, saline or lidocaine. The solution irritates the affected connective tissue, stimulating the body’s own natural healing mechanisms to encourage growth of new normal ligament or tendon fibers.

Electromagnetic Transduction Therapy (EMTT)

Professional associations and memberships

Dr. Kalika is currently a certified member of:


American Institute of Ultrasound Medicine


Active member of ISMST

International Society of Extra Corporeal Shockwave Therapy


Active member of GCMAS

Gait and Clinical Movement Analysis Society


Active member of NASS

North American Spine Society


Active member of IADMS

International Association of Dance Medicine and Science


Active member of Virtual Rehabilitation Society


Active member of ASRA

American Society of Regional Anesthesia and Pain Medicine


American Academy

Association of Orthopedic Medicine


Active member of Interventional Orthobiologics Foundation

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Get the Best Prolozone Therapy in NYC

Athletic injuries that are slow to heal can take you out of the game or away from your favorite physical activities for months on end. For athletes who compete at elite levels, chronic injuries can be career-ending and life-altering.

The sports medicine specialists at NYDNRehab have helped hundreds of athletes to rehabilitate injuries and enhance performance. Our ongoing quest for the latest technologies and therapies keeps us on the cutting edge of rehabilitative medicine.

Prolotherapy is just one of the many rehabilitative options we offer at NYDNRehab. Our commitment to excellence ensures that you will receive the very best care, and recover in the least amount of time possible. Contact NYDNRehab today, and get on the road to recovery so you can get back out there!

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    Dr. Lev Kalika
    Dr. Lev Kalika

    Clinical director & DC RMSK

    Our Specialists

    Dr. Mikhail Bernshteyn MD (Internist)
    Dr. Michael Goynatsky DPT
    Dr. Daniela Escudero DPT
    Dr. Michelle Agyakwah DC
    Dr. Tatyana Kapustina L. Ac.

    Range of Available Unique Physical Therapy
    Treatments at Nydnrehab


    In this instance, an athlete was originally diagnosed with minor quadriceps muscle strain and was treated for four weeks, with unsatisfactory results. When he came to our clinic, the muscle was not healing, and the patients’ muscle tissue had already begun to atrophy.

    Upon examination using MSUS, we discovered that he had a full muscle thickness tear that had been overlooked by his previous provider. To mitigate damage and promote healing, surgery should have been performed immediately after the injury occurred. Because of misdiagnosis and inappropriate treatment, the patient now has permanent damage that cannot be corrected.

    The most important advantage of Ultrasound over MRI imaging is its ability to zero in on the symptomatic region and obtain imaging, with active participation and feedback from the patient. Using dynamic MSUS, we can see what happens when patients contract their muscles, something that cannot be done with MRI. From a diagnostic perspective, this interaction is invaluable.

    Dynamic ultrasonography examination demonstrating
    the full thickness tear and already occurring muscle atrophy
    due to misdiagnosis and not referring the patient
    to proper diagnostic workup

    Demonstration of how very small muscle defect is made and revealed
    to be a complete tear with muscle contraction
    under diagnostic sonography (not possible with MRI)


    Complete tear of rectus femoris
    with large hematoma (blood)


    Separation of muscle ends due to tear elicited
    on dynamic sonography examination

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